The JAMA Neurology journal published an article and the studies objective was to understand the exact prevalence, severity, and underlying biological mechanisms of abnormal eating behaviors that are common in patients with frontotemporal dementia.
Forty-nine patients with dementia were recruited, and their eating behaviour was compared with that of 25 healthy controls. The study was conducted from November 1, 2013, through May 31, 2015, and data analysed from June 1 to August 31, 2015. The mean ages of patients involved ranged from 62 (8.3) to 66 (8.4) years.
Voxel-based morphometry analysis of whole-brain 3-T high-resolution brain magnetic resonance imaging was used to determine the gray matter density changes across groups and their relations to eating behaviors.
Concluding that delineating the neural networks involved in mediating these changes in eating behavior may enable treatment of these features in patients with complex medical needs and aid in our understanding of structures that control eating behavior in patients with FTD and healthy individuals.
Ahmed, R. M., Irish, M., Henning, E., Dermody, N., Bartley, L., Kiernan, M. C., … Hodges, J. R. (2016). Assessment of eating behavior disturbance and associated neural networks in Frontotemporal dementia. JAMA Neurology, 73(3), 282. doi:10.1001/jamaneurol.2015.4478